About
DRUG-INDUCED NUTRIENT DEPLETION

“You cannot poison a crucial enzyme, block an important receptor, or interfere with a metabolic function for the long term and expect a good result.”- David Brownstein, M.D. Drugs That Don’t Work and Natural Therapies That Do

The issue that we need to consider is not whether alternative or complementary therapies work better than prescription medications. Instead, we need to look at how our medications work in our bodies and their effect on various essential pathways. If you look at the mechanism of action for many of our drugs, you will see terms like “inhibitor,” “modifier,” “agonist,” and other similar terms. These descriptions would indicate a change in a metabolic pathway created by the presence of a drug. When inserted into our essential metabolic pathways, drugs can affect nutrient absorption, synthesis, transport, storage, metabolism and excretion. This is the basis of Dr. Brownstein’s statement. What are the ultimate nutritional and metabolic deficiencies that can occur in the bodyfrom long-term usage of drugs? Is it possible that drugs, when taken over time, have the potential to create greater problems than the disease state for which they were initially prescribed?

Physicians and pharmacists need to take into consideration the potential nutrient depletions which accompany long-term medication administration. These nutrient depletions can undermine the patient’s health and well-being. Nutrients are critical to normal body function! The various vitamins, minerals and other micronutrients provided in our diet fuel the thousands of metabolic processes that occur in our bodies. They are essential for life as we know it.

We know that drug-induced nutrient depletions can be multifactorial. We can identify the nutrient depletions accompanying a particular drug. But what happens when multiple drugs are inserted into the various metabolic pathways in the body? What is the total cost to our nutrient uptake? We also know that problems from drug-induced nutrient depletions can arise several months after beginning a drug. When these problems arise, they may not be connected to the introduction of a medication months earlier. Instead, the problems may be viewed by the physician as a new complaint, creating the addition of yet another drug to the patient’s regimen.

Drug-induced nutrient depletions are present in most of our popular drugs. Patients should review their medication profile with their pharmacist, and utilize appropriate nutritional supplementation when necessary. Products such as the “statin” drugs, estrogens, H2 blockers, PPIs, antibiotics and a host of other
commonly prescribed drugs should be accompanied by Coenzyme Q-10, B-vitamins, folic acid, magnesium, vitamin K and probiotics, just to name a few of the protective supplements. Advising you on your potential drug-induced nutrient depletions is your pharmacist’s responsibility. Inform your pharmacist of all of the medications you are taking, both prescription and over-the-counter

DEPLETING DRUGS DEPLETED NUTRIENT RECOMMENDED SUPPLEMENTS
Female Hormones • Anti-Inflammatories
Antibiotics
B Vitamins (B1, B2, B3, B6) CoEnzyme-B • Vitamin B-Complex 100 mg
Long-Acting Formula
Female Hormones • Anti-Ulcer & GERD Drugs
Anti-Diabetic Drugs • Aspirin • Stomach Acid
Drugs
Vitamin B-12 Methylcobalamin B-12 Spray
Methyl B-12 Lozenges
Anti-Ulcer Drugs • Anti-Hypertensives
Anti-Inflammatories • Stomach Acid Drugs
Calcium Calcium & Magnesium Plus
Calcium & Magnesium Citrates
Female Hormones • Beta Blockers
Cholesterol-Lowering Drugs • Anti-Diabetic
Drugs
Anti-Hypertensives
Coenzyme Q-10 CoEnzyme Q10 100 mg • Ubiquinol CoQH
100 mg Note: 100 mg/day/per depleting drug
used
Anti-Ulcer & GERD Drugs • Anti-Convulsants
Stomach Acid Drugs
AVitamin D (40-75% of
individuals are deficient
in vitamin D)
Vitamin D3 1000 IU • Vitamin D 5000 IU
Vitamin D3 Drops 2000 IU
Female Hormones • Anti-Ulcer & GERD
Drugs Anti-Diabetic Drugs • AntiInflammatories Stomach Acid Drugs •
Antibiotics
Folic Acid Folic Acid 800 mcg with Vitamin B-12
5-MTHF 1 mg
Antibiotics • Anti-Convulsants
Anti-Hypertensives • Anti-Inflammatories
Vitamin K Vitamin K2
Vitamin D3 & K2 Emulsion
Female Hormones • Anti-Hypertensives
Lanoxin • Benzodiazepines
Magnesium (68-80% of
individuals are deficient
in magnesium)
Magnesium Glycinate Powder 1000 mg
Magnesium Chelate 400 mg
Magnesium & Potassium Aspartate
Benzodiazepines • Beta Blockers Melatonin Melatonin Liposomal Spray • Melatonin
3 mg Long Acting • Melatonin 3 mg with
Vitamin B-6
Antibiotics Gut Flora (70% of immunity
is in the gut)
Extra Strength Probiotic • FOS Powder
Female Hormones • Anti-Hypertensives
Anti-Ulcer & GERD Drugs
Zinc (Essential for insulin,
wound healing, and taste)
Zinc 20 mg • Zinc Lozenges

Drug-induced nutrient depletion occurs when the medications we take for our various health issues block the absorption, storage, metabolism, or synthesis of essential nutrients in the body. When nutrients are blocked or depleted over time, health problems can develop secondary to those depletions. Many of the most popular medications prescribed today can create these drug-induced nutrient depletions.

Drug-induced nutrient depletion occurs when the medications we take for our various health issues block the absorption, storage, metabolism, or synthesis of essential nutrients in the body. When nutrients are blocked or depleted over time, health problems can develop secondary to those depletions. Many of the most popular medications prescribed today can create these drug-induced nutrient depletions.

What can be done about this problem? Your pharmacist is specially trained to recommend supplements that will help offset drug-induced nutrient depletions and their resultant health problems. It is important that you share with your pharmacist all of the medications you are taking – both prescription and over-the-counter. Are you using any of the above medications?